Domain Mapping activated or deactivated by an individual site

Replies: 1

After I follow the instructions in this post:
https://wordpress.org/support/topic/howto-domain-mapping-without-a-plugin-instructions?replies=13

Everything works as it should But now there’s something I do not understand, How do I manage Plugins to be activated or deactivated by an individual site?

https://wordpress.org/plugins/wordpress-mu-domain-mapping/